Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children’s Oncology Group

BACKGROUND: Abnormal DNA methylation may be important in germ cell tumour (GCT) aetiology, as germ cells undergo complete epigenetic reprogramming during development. GCTs show differences in global and promoter methylation patterns by histologic subtype. We conducted an epigenome-wide study to iden...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Williams, Lindsay A., Mills, Lauren, Hooten, Anthony J., Langer, Erica, Roesler, Michelle, Frazier, A. Lindsay, Krailo, Mark, Nelson, Heather H., Bestrashniy, Jessica, Amatruda, James F., Poynter, Jenny N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189207/
https://ncbi.nlm.nih.gov/pubmed/30287918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0277-5
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