Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology

BACKGROUND: Alterations in methylation patterns, miRNA expression, and stem cell protein expression occur in germ cell tumors (GCTs). Our goal is to integrate molecular data across platforms to identify molecular signatures in the three main histologic subtypes of Type I and Type II GCTs (yolk sac t...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Poynter, Jenny N., Bestrashniy, Jessica R. B. M., Silverstein, Kevin A. T., Hooten, Anthony J., Lees, Christopher, Ross, Julie A., Tolar, Jakub
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619074/
https://ncbi.nlm.nih.gov/pubmed/26497383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1796-6
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