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Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children’s Oncology Group

BACKGROUND: Abnormal DNA methylation may be important in germ cell tumour (GCT) aetiology, as germ cells undergo complete epigenetic reprogramming during development. GCTs show differences in global and promoter methylation patterns by histologic subtype. We conducted an epigenome-wide study to iden...

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Podrobná bibliografie
Vydáno v:Br J Cancer
Hlavní autoři: Williams, Lindsay A., Mills, Lauren, Hooten, Anthony J., Langer, Erica, Roesler, Michelle, Frazier, A. Lindsay, Krailo, Mark, Nelson, Heather H., Bestrashniy, Jessica, Amatruda, James F., Poynter, Jenny N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189207/
https://ncbi.nlm.nih.gov/pubmed/30287918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0277-5
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