Different Angiogenic Potential in Low and High Grade Sporadic Clear Cell Renal Cell Carcinoma Is Not Related to Alterations in the von Hippel–Lindau Gene

Background: von Hippel–Lindau (VHL) inactivation is common in sporadic clear cell renal cell carcinomas (ccRCC). pVHL is part of the ubiquitin ligase complex that targets the alpha subunits of hypoxia-inducible transcription factor (HIF) for degradation under well-oxygenated conditions. In the absen...

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Publicado no:Cell Oncol
Main Authors: Baldewijns, Marcella M., van Vlodrop, Iris J. H., Smits, Kim M., Vermeulen, Peter B., Van den Eynden, Gert G., Schot, Fiona, Roskams, Tania, van Poppel, Hein, van Engeland, Manon, de Bruïne, Adriaan P.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619045/
https://ncbi.nlm.nih.gov/pubmed/19759417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2009-0482
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