High-grade clear cell renal cell carcinoma has a higher angiogenic activity than low-grade renal cell carcinoma based on histomorphological quantification and qRT–PCR mRNA expression profile

Clear cell renal cell carcinoma (CC-RCC) is a highly vascularised tumour and is therefore an attractive disease to study angiogenesis and to test novel angiogenesis inhibitors in early clinical development. Endothelial cell proliferation plays a pivotal role in the process of angiogenesis. The aim o...

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Autors principals: Baldewijns, M M, Thijssen, V L, Van den Eynden, G G, Van Laere, S J, Bluekens, A M, Roskams, T, van Poppel, H, De Bruïne, A P, Griffioen, A W, Vermeulen, P B
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2007
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359956/
https://ncbi.nlm.nih.gov/pubmed/17505508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603796
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