CD39 Expression Identifies Terminally Exhausted CD8(+) T Cells

Exhausted T cells express multiple co-inhibitory molecules that impair their function and limit immunity to chronic viral infection. Defining novel markers of exhaustion is important both for identifying and potentially reversing T cell exhaustion. Herein, we show that the ectonucleotidse CD39 is a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Gupta, Prakash K., Godec, Jernej, Wolski, David, Adland, Emily, Yates, Kathleen, Pauken, Kristen E., Cosgrove, Cormac, Ledderose, Carola, Junger, Wolfgang G., Robson, Simon C., Wherry, E. John, Alter, Galit, Goulder, Philip J. R., Klenerman, Paul, Sharpe, Arlene H., Lauer, Georg M., Haining, W. Nicholas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618999/
https://ncbi.nlm.nih.gov/pubmed/26485519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005177
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