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Histone Deacetylase Inhibitors Inhibit Rhabdomyosarcoma by Reactive Oxygen Species-Dependent Targeting of Specificity Protein Transcription Factors

The two major types of rhabdomyosarcomas (RMS) are predominantly diagnosed in children, namely embryonal (ERMS) and alveolar (ARMS) RMS and patients are treated with cytotoxic drugs which results in multiple toxic side effects later in life. Therefore, development of innovative chemotherapeutic stra...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Hedrick, Erik, Crose, Lisa, Linardic, Corinne M., Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618474/
https://ncbi.nlm.nih.gov/pubmed/26162688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0148
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