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Piperlongumine Induces Reactive Oxygen Species (ROS)-dependent Downregulation of Specificity Protein Transcription Factors

Piperlongumine is a natural product found in the plant species Piper longum and this compound exhibits potent anticancer activity in multiple tumor types and has been characterized as an inducer of reactive oxygen species (ROS). Treatment of Panc1 and L3.6pL pancreatic, A549 lung, 786-O kidney, and...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Karki, Keshav, Hedrick, Erik, Kasiappan, Ravi, Jin, Un-Ho, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357769/
https://ncbi.nlm.nih.gov/pubmed/28673967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0053
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