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Generation of Reactive Oxygen Species during Apoptosis Induced by DNA-Damaging Agents and/or Histone Deacetylase Inhibitors

Reactive oxygen species play an important role in the process of apoptosis in many cell types. In this paper, we analyzed the role of ROS in DNA-damaging agents (actinomycin D or decitabine), which induced apoptosis of leukemia cell line CML-T1 and normal peripheral blood lymphocytes (PBL). The poss...

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Detalhes bibliográficos
Main Authors: Brodská, Barbora, Holoubek, Aleš
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178180/
https://ncbi.nlm.nih.gov/pubmed/21949898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/253529
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