Promoter Methylation Precedes Chromosomal Alterations in Colorectal Cancer Development

Background: Colorectal cancers are characterized by genetic and epigenetic alterations. This study aimed to explore the timing of promoter methylation and relationship with mutations and chromosomal alterations in colorectal carcinogenesis. Methods: In a series of 47 nonprogressed adenomas, 41 progr...

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Bibliografske podrobnosti
izdano v:Cell Oncol
Main Authors: Derks, Sarah, Postma, Cindy, Moerkerk, Peter T. M., van den Bosch, Sandra M., Carvalho, Beatriz, Hermsen, Mario A. J. A., Giaretti, Walter, Herman, James G., Weijenberg, Matty P., de Bruïne, Adriaan P., Meijer, Gerrit A., van Engeland, Manon
Format: Artigo
Jezik:Inglês
Izdano: IOS Press 2006
Teme:
Other
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618222/
https://ncbi.nlm.nih.gov/pubmed/17167178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2006/846251
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