Promoter Methylation Precedes Chromosomal Alterations in Colorectal Cancer Development

Background: Colorectal cancers are characterized by genetic and epigenetic alterations. This study aimed to explore the timing of promoter methylation and relationship with mutations and chromosomal alterations in colorectal carcinogenesis. Methods: In a series of 47 nonprogressed adenomas, 41 progr...

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發表在:Cell Oncol
Main Authors: Derks, Sarah, Postma, Cindy, Moerkerk, Peter T. M., van den Bosch, Sandra M., Carvalho, Beatriz, Hermsen, Mario A. J. A., Giaretti, Walter, Herman, James G., Weijenberg, Matty P., de Bruïne, Adriaan P., Meijer, Gerrit A., van Engeland, Manon
格式: Artigo
語言:Inglês
出版: IOS Press 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618222/
https://ncbi.nlm.nih.gov/pubmed/17167178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2006/846251
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