Promoter Methylation Precedes Chromosomal Alterations in Colorectal Cancer Development

Background: Colorectal cancers are characterized by genetic and epigenetic alterations. This study aimed to explore the timing of promoter methylation and relationship with mutations and chromosomal alterations in colorectal carcinogenesis. Methods: In a series of 47 nonprogressed adenomas, 41 progr...

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Detalhes bibliográficos
Publicado no:Cell Oncol
Main Authors: Derks, Sarah, Postma, Cindy, Moerkerk, Peter T. M., van den Bosch, Sandra M., Carvalho, Beatriz, Hermsen, Mario A. J. A., Giaretti, Walter, Herman, James G., Weijenberg, Matty P., de Bruïne, Adriaan P., Meijer, Gerrit A., van Engeland, Manon
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618222/
https://ncbi.nlm.nih.gov/pubmed/17167178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2006/846251
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