Promoter Methylation Precedes Chromosomal Alterations in Colorectal Cancer Development

Background: Colorectal cancers are characterized by genetic and epigenetic alterations. This study aimed to explore the timing of promoter methylation and relationship with mutations and chromosomal alterations in colorectal carcinogenesis. Methods: In a series of 47 nonprogressed adenomas, 41 progr...

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Détails bibliographiques
Publié dans:Cell Oncol
Auteurs principaux: Derks, Sarah, Postma, Cindy, Moerkerk, Peter T. M., van den Bosch, Sandra M., Carvalho, Beatriz, Hermsen, Mario A. J. A., Giaretti, Walter, Herman, James G., Weijenberg, Matty P., de Bruïne, Adriaan P., Meijer, Gerrit A., van Engeland, Manon
Format: Artigo
Langue:Inglês
Publié: IOS Press 2006
Sujets:
Other
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618222/
https://ncbi.nlm.nih.gov/pubmed/17167178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2006/846251
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