Intratumor Heterogeneity of K-Ras and p53 Mutations among Human Colorectal Adenomas Containing Early Cancer

The molecular pathways and the timing of genetic events during human colorectal carcinogenesis are still not fully understood. We have addressed the intratumor heterogeneity of the mutational status of the k‐ras oncogene and of the p53 oncosuppressor gene during the adenoma–carcinoma sequence by inv...

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Publicado en:Anal Cell Pathol
Main Authors: Giaretti, Walter, Macciocu, Barbara, Geido, Elio, Hermsen, Mario, Postma, Cindy, Baak, Jan, Williams, Richard, Meijer, Gerrit
Formato: Artigo
Idioma:Inglês
Publicado: IOS Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615987/
https://ncbi.nlm.nih.gov/pubmed/11310641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2000/747524
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