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Intratumor Heterogeneity of K-Ras and p53 Mutations among Human Colorectal Adenomas Containing Early Cancer

The molecular pathways and the timing of genetic events during human colorectal carcinogenesis are still not fully understood. We have addressed the intratumor heterogeneity of the mutational status of the k‐ras oncogene and of the p53 oncosuppressor gene during the adenoma–carcinoma sequence by inv...

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Publicat a:Anal Cell Pathol
Autors principals: Giaretti, Walter, Macciocu, Barbara, Geido, Elio, Hermsen, Mario, Postma, Cindy, Baak, Jan, Williams, Richard, Meijer, Gerrit
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615987/
https://ncbi.nlm.nih.gov/pubmed/11310641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2000/747524
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