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Decreased reactivation of a herpes simplex virus type 1 (HSV-1) latency associated transcript (LAT) mutant using the in vivo mouse UV-B model of induced reactivation

Blinding ocular herpetic disease in humans is due to herpes simplex virus type 1 (HSV-1) reactivations from latency, rather than to primary acute infection. The cellular and molecular mechanisms that control the HSV-1 latency-reactivation cycle remain to be fully elucidated. The aim of this study wa...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurovirol
Hauptverfasser: BenMohamed, Lbachir, Osorio, Nelson, Srivastava, Ruchi, Khan, Arif A., Simpson, Jennifer L., Wechsler, Steven L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618093/
https://ncbi.nlm.nih.gov/pubmed/26002839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-015-0348-9
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