Prior Corneal Scarification and Injection of Immune Serum are Not Required Before Ocular HSV-1 Infection for UV-B-Induced Virus Reactivation and Recurrent Herpetic Corneal Disease in Latently Infected Mice

PURPOSE: Blinding ocular herpetic disease in humans is due to spontaneous reactivation of herpes simplex virus type 1 (HSV-1) from latency, rather than to primary acute infection. Mice latently infected with HSV-1 undergo little or no in vivo spontaneous reactivation with accompanying virus shedding...

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Detalhes bibliográficos
Publicado no:Curr Eye Res
Main Authors: BenMohamed, Lbachir, Osorio, Nelson, Khan, Arif A., Srivastava, Ruchi, Huang, Lei, Krochmal, John J., Garcia, Jairo M., Simpson, Jennifer L., Wechsler, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349863/
https://ncbi.nlm.nih.gov/pubmed/26398722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02713683.2015.1061024
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