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Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling
Notch receptors direct the differentiation of T helper (T(H)) cell subsets, but their influence on regulatory T (T(reg)) cell responses is obscure. We here report that lineage-specific deletion of components of the Notch pathway enhanced T(reg) cell-mediated suppression of T(H)1 responses, and prote...
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| Publicado no: | Nat Immunol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618075/ https://ncbi.nlm.nih.gov/pubmed/26437242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3288 |
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