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Regulatory T Cells: Exosomes Deliver Tolerance

T regulatory (Treg) cells enforce peripheral tolerance through regulation of diverse immune responses in a context-dependent manner. Okoye et al show one way in which Treg cells suppress Th1 cell responses is through non-autonomous gene silencing mediated by microRNA-containing exosomes.

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chatila, Talal A., Williams, Calvin B.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130330/
https://ncbi.nlm.nih.gov/pubmed/25035945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.07.001
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