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Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase

Identifying enzymes that, once introduced in cancer cells, lead to an increased efficiency of treatment constitutes an important goal for biomedical applications. Using an original procedure whereby mutant genes are generated based on the use of conditional lentivector genome mobilisation, we recent...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Coulibaly, Safiatou T., Rossolillo, Paola, Winter, Flore, Kretzschmar, Franziska K., Brayé, Mélanie, Martin, Darren P., Lener, Daniela, Negroni, Matteo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618062/
https://ncbi.nlm.nih.gov/pubmed/26485161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140741
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