NKNK: a New Essential Motif in the C-Terminal Domain of HIV-1 Group M Integrases

Using coevolution network interference based on comparison of two phylogenetically distantly related isolates, one from the main group M and the other from the minor group O of HIV-1, we identify, in the C-terminal domain (CTD) of integrase, a new functional motif constituted by four noncontiguous a...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kanja, Marine, Cappy, Pierre, Levy, Nicolas, Oladosu, Oyndamola, Schmidt, Sylvie, Rossolillo, Paola, Winter, Flore, Gasser, Romain, Moog, Christiane, Ruff, Marc, Negroni, Matteo, Lener, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527040/
https://ncbi.nlm.nih.gov/pubmed/32727879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01035-20
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