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Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase

Identifying enzymes that, once introduced in cancer cells, lead to an increased efficiency of treatment constitutes an important goal for biomedical applications. Using an original procedure whereby mutant genes are generated based on the use of conditional lentivector genome mobilisation, we recent...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Coulibaly, Safiatou T., Rossolillo, Paola, Winter, Flore, Kretzschmar, Franziska K., Brayé, Mélanie, Martin, Darren P., Lener, Daniela, Negroni, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618062/
https://ncbi.nlm.nih.gov/pubmed/26485161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140741
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