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Potent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine Kinase

Identifying enzymes that, once introduced in cancer cells, lead to an increased efficiency of treatment constitutes an important goal for biomedical applications. Using an original procedure whereby mutant genes are generated based on the use of conditional lentivector genome mobilisation, we recent...

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Pubblicato in:PLoS One
Autori principali: Coulibaly, Safiatou T., Rossolillo, Paola, Winter, Flore, Kretzschmar, Franziska K., Brayé, Mélanie, Martin, Darren P., Lener, Daniela, Negroni, Matteo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618062/
https://ncbi.nlm.nih.gov/pubmed/26485161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140741
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