Loading...
A Mouse Model of Human Congenital Heart Disease: Progressive Atrioventricular Block Induced by a Heterozygous Nkx2-5 Homeodomain Missense Mutation
BACKGROUND: Heterozygous human NKX2-5 homeodomain (DNA binding domain) missense mutations are highly penetrant for varied congenital heart defects, including progressive atrioventricular block (AVB) requiring pacemaker implantation. We recently replicated this genetic defect in a murine knock-in mod...
Na minha lista:
| Udgivet i: | Circ Arrhythm Electrophysiol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618020/ https://ncbi.nlm.nih.gov/pubmed/26226998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.115.002720 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|