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Crystallization and preliminary X-ray analysis of the NKX2.5 homeodomain in complex with DNA

As part of an effort to elucidate the molecular basis for the pathogenesis of NKX2.5 mutations in congenital heart disease using X-ray crystallography, the NKX2.5 homeodomain has been crystallized in complex with a specific DNA element, the −242 promoter region of atrial natriuretic factor. Crystals...

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Autori principali: Genis, Caroli, Scone, Peyton, Kasahara, Hideko, Nam, Hyun-Joo
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581709/
https://ncbi.nlm.nih.gov/pubmed/18997347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108033447
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