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Crystallization and preliminary X-ray analysis of the NKX2.5 homeodomain in complex with DNA
As part of an effort to elucidate the molecular basis for the pathogenesis of NKX2.5 mutations in congenital heart disease using X-ray crystallography, the NKX2.5 homeodomain has been crystallized in complex with a specific DNA element, the −242 promoter region of atrial natriuretic factor. Crystals...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
International Union of Crystallography
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2581709/ https://ncbi.nlm.nih.gov/pubmed/18997347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108033447 |
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