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Crystallization and preliminary X-ray analysis of the cardiac transcription factor complex of NKX2.5 and TBX5 with DNA

Heart development depends on timely expression of genes regulated by combinatorial interactions of master cardiac transcription factors. To elucidate the molecular basis of their interactions, a ternary complex of cardiac transcription factors, NKX2.5 and TBX5, and their target DNA was studied using...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pradhan, Lagnajeet, Gopal, Sunil, Nam, Hyun-Joo
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014325/
https://ncbi.nlm.nih.gov/pubmed/24817716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14006761
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