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Streptococcus pyogenes Sortase Mutants Are Highly Susceptible to Killing by Host Factors Due to Aberrant Envelope Physiology

Cell wall anchored virulence factors are critical for infection and colonization of the host by Gram-positive bacteria. Such proteins have an N-terminal leader sequence and a C-terminal sorting signal, composed of an LPXTG motif, a hydrophobic stretch, and a few positively charged amino acids. The s...

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Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Raz, Assaf, Tanasescu, Ana-Maria, Zhao, Anna M., Serrano, Anna, Alston, Tricia, Sol, Asaf, Bachrach, Gilad, Fischetti, Vincent A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617865/
https://ncbi.nlm.nih.gov/pubmed/26484774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140784
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