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Sortase A localizes to distinct foci on the Streptococcus pyogenes membrane

Cell wall peptidoglycan-anchored surface proteins are essential virulence factors in many gram-positive bacteria. The attachment of these proteins to the peptidoglycan is achieved through a transpeptidation reaction, whereby sortase cleaves a conserved C-terminal LPXTG motif and covalently attaches...

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Bibliographic Details
Main Authors: Raz, Assaf, Fischetti, Vincent A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587614/
https://ncbi.nlm.nih.gov/pubmed/19017791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808301105
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