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Chromatin architecture of the Pitx2 locus requires CTCF and Pitx2 dependent asymmetry that mirrors embryonic gut laterality
Expression of Pitx2 on the left side of the embryo patterns left-right (LR) organs including the dorsal mesentery (DM), whose asymmetric cell behavior directs gut looping. Despite the importance of organ laterality, chromatin-level regulation of Pitx2 remains undefined. Here we show that genes immed...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617833/ https://ncbi.nlm.nih.gov/pubmed/26411685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.075 |
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