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Integration of L-R Pitx2 transcription and Wnt signaling drives asymmetric gut morphogenesis via Daam2
A critical aspect of gut morphogenesis is initiation of a leftward tilt. Failure to do so leads to gut malrotation and volvulus. The direction of tilt is specified by asymmetric cell behaviors within the dorsal mesentery (DM), which suspends the gut tube, and is downstream of Pitx2, the key transcri...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965270/ https://ncbi.nlm.nih.gov/pubmed/24091014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.07.019 |
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