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Shroom3 and a Pitx2-N-cadherin pathway function cooperatively to generate asymmetric cell shape changes during gut morphogenesis

The cytoskeletal protein Shroom3 is a potent inducer of epithelial cell shape change and is required for lens and neural plate morphogenesis. Analysis of gut morphogenesis in Shroom3 deficient mouse embryos revealed that the direction of gut rotation is also disrupted. It was recently established th...

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Detalhes bibliográficos
Main Authors: Plageman, Timothy F., Zacharias, Amanda. L, Gage, Phillip J., Lang., Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619216/
https://ncbi.nlm.nih.gov/pubmed/21726547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.06.027
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