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The left-right Pitx2 pathway drives organ-specific arterial and lymphatic development in the intestine

The dorsal mesentery (DM) is the major conduit for blood and lymphatic vessels in the gut. The mechanisms underlying their morphogenesis are challenging to study and remain unknown. Here we show that arteriogenesis in the DM begins during gut rotation and proceeds strictly on the left side, dependen...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Mahadevan, Aparna, Welsh, Ian C., Sivakumar, Aravind, Gludish, David W., Shilvock, Abigail R., Noden, Drew M., Kurpios, Natasza A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4326534/
https://ncbi.nlm.nih.gov/pubmed/25482882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.11.002
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