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Cables1 controls p21/Cip1 protein stability by antagonizing proteasome subunit alpha type 3
The cyclin-dependent kinase inhibitor 1A (CDKN1A), p21/Cip1, is a vital cell cycle regulator, dysregulation of which has been associated with a large number of human malignancies. One critical mechanism that controls p21 function is through its degradation, which allows the activation of its associa...
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| Vydáno v: | Oncogene |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617825/ https://ncbi.nlm.nih.gov/pubmed/24975575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.171 |
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