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Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1)
Clinical application of potent anthracycline anticancer drugs, especially doxorubicin (DOX), is limited by a toxic cardiac side effect that is not fully understood and preventive strategies are yet to be established. Studies in genetically modified mice have demonstrated that focal adhesion kinase (...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4237309/ https://ncbi.nlm.nih.gov/pubmed/24342076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.12.002 |
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