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Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1)

Clinical application of potent anthracycline anticancer drugs, especially doxorubicin (DOX), is limited by a toxic cardiac side effect that is not fully understood and preventive strategies are yet to be established. Studies in genetically modified mice have demonstrated that focal adhesion kinase (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Cell Cardiol
Prif Awduron: Cheng, Zhaokang, DiMichele, Laura A., Rojas, Mauricio, Vaziri, Cyrus, Mack, Christopher P., Taylor, Joan M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237309/
https://ncbi.nlm.nih.gov/pubmed/24342076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.12.002
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