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Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1)

Clinical application of potent anthracycline anticancer drugs, especially doxorubicin (DOX), is limited by a toxic cardiac side effect that is not fully understood and preventive strategies are yet to be established. Studies in genetically modified mice have demonstrated that focal adhesion kinase (...

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Foilsithe in:J Mol Cell Cardiol
Main Authors: Cheng, Zhaokang, DiMichele, Laura A., Rojas, Mauricio, Vaziri, Cyrus, Mack, Christopher P., Taylor, Joan M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237309/
https://ncbi.nlm.nih.gov/pubmed/24342076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2013.12.002
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