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Myocyte-Restricted Focal Adhesion Kinase Deletion Attenuates Pressure Overload-Induced Hypertrophy

Focal adhesion kinase (FAK) is a ubiquitously expressed cytoplasmic tyrosine kinase strongly activated by integrins and neurohumoral factors. Previous studies have shown that cardiac FAK activity is enhanced by hypertrophic stimuli before the onset of overt hypertrophy. Herein, we report that condit...

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Main Authors: DiMichele, Laura A., Doherty, Jason T., Rojas, Mauricio, Beggs, Hilary E., Reichardt, Louis F., Mack, Christopher P., Taylor, Joan M.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2693055/
https://ncbi.nlm.nih.gov/pubmed/16902179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000240498.44752.d6
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