Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

In response to αβ1 integrin signaling, transducers such as focal adhesion kinase (FAK) become activated, relaying to specific machineries and triggering distinct cellular responses. By conditionally ablating Fak in skin epidermis and culturing Fak-null keratinocytes, we show that FAK is dispensable...

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Bibliografiska uppgifter
Huvudupphovsmän: Schober, Markus, Raghavan, Srikala, Nikolova, Maria, Polak, Lisa, Pasolli, H. Amalia, Beggs, Hilary E., Reichardt, Louis F., Fuchs, Elaine
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2007
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064024/
https://ncbi.nlm.nih.gov/pubmed/17325207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200608010
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