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Human tolerogenic dendritic cells produce IL-35 in the absence of other IL-12 family members

IL-35 is a cytokine of the IL-12 family, existing as a heterodimer of IL-12p35 and Ebi3. IL-35 has anti-inflammatory properties and is produced by regulatory T cells in humans and mice, where it is required for optimal suppression of immune responses. Distinct from other IL-12 cytokines, the express...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Dixon, Karen O., van der Kooij, Sandra W., Vignali, Dario A.A., van Kooten, Cees
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617619/
https://ncbi.nlm.nih.gov/pubmed/25820702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201445217
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