Interleukin-35-Producing CD8α(+) Dendritic Cells Acquire a Tolerogenic State and Regulate T Cell Function

Dendritic cells (DCs) play a central role in shaping immunogenic as well as tolerogenic adaptive immune responses and thereby dictate the outcome of adaptive immunity. Here, we report the generation of a CD8α(+) DC line constitutively secreting the tolerogenic cytokine interleukin (IL)-35. IL-35 sec...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Haller, Sergio, Duval, Anaïs, Migliorini, Romain, Stevanin, Mathias, Mack, Vanessa, Acha-Orbea, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5296329/
https://ncbi.nlm.nih.gov/pubmed/28228759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00098
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