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A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C

The regulation of protein and mRNA turnover is essential for many cellular processes. We recently showed that ubiquitin—traditionally linked to protein degradation—directly regulates the degradation of mRNAs through the action of a newly identified family of RNA-binding E3 ubiquitin ligases. How ubi...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Cano, Florencia, Rapiteanu, Radu, Sebastiaan Winkler, G., Lehner, Paul J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617606/
https://ncbi.nlm.nih.gov/pubmed/26471122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9670
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