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Targeting mitochondrial complex I using BAY 87-2243 reduces melanoma tumor growth
BACKGROUND: Numerous studies have demonstrated that functional mitochondria are required for tumorigenesis, suggesting that mitochondrial oxidative phosphorylation (OXPHOS) might be a potential target for cancer therapy. In this study, we investigated the effects of BAY 87-2243, a small molecule tha...
שמור ב:
| הוצא לאור ב: | Cancer Metab |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615872/ https://ncbi.nlm.nih.gov/pubmed/26500770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-015-0138-0 |
| תגים: |
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