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Click chemistry armed enzyme-linked immunosorbent assay to measure palmitoylation by hedgehog acyltransferase

Hedgehog signaling is critical for correct embryogenesis and tissue development. However, on maturation, signaling is also found to be aberrantly activated in many cancers. Palmitoylation of the secreted signaling protein sonic hedgehog (Shh) by the enzyme hedgehog acyltransferase (Hhat) is required...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Anal Biochem
Main Authors: Lanyon-Hogg, Thomas, Masumoto, Naoko, Bodakh, George, Konitsiotis, Antonio D., Thinon, Emmanuelle, Rodgers, Ursula R., Owens, Raymond J., Magee, Anthony I., Tate, Edward W.
פורמט: Artigo
שפה:Inglês
יצא לאור: Academic Press 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615133/
https://ncbi.nlm.nih.gov/pubmed/26334609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.08.025
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