Click chemistry armed enzyme-linked immunosorbent assay to measure palmitoylation by hedgehog acyltransferase

Hedgehog signaling is critical for correct embryogenesis and tissue development. However, on maturation, signaling is also found to be aberrantly activated in many cancers. Palmitoylation of the secreted signaling protein sonic hedgehog (Shh) by the enzyme hedgehog acyltransferase (Hhat) is required...

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Detalhes bibliográficos
Publicado no:Anal Biochem
Main Authors: Lanyon-Hogg, Thomas, Masumoto, Naoko, Bodakh, George, Konitsiotis, Antonio D., Thinon, Emmanuelle, Rodgers, Ursula R., Owens, Raymond J., Magee, Anthony I., Tate, Edward W.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615133/
https://ncbi.nlm.nih.gov/pubmed/26334609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.08.025
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