Click chemistry armed enzyme-linked immunosorbent assay to measure palmitoylation by hedgehog acyltransferase

Hedgehog signaling is critical for correct embryogenesis and tissue development. However, on maturation, signaling is also found to be aberrantly activated in many cancers. Palmitoylation of the secreted signaling protein sonic hedgehog (Shh) by the enzyme hedgehog acyltransferase (Hhat) is required...

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Bibliografiset tiedot
Julkaisussa:Anal Biochem
Päätekijät: Lanyon-Hogg, Thomas, Masumoto, Naoko, Bodakh, George, Konitsiotis, Antonio D., Thinon, Emmanuelle, Rodgers, Ursula R., Owens, Raymond J., Magee, Anthony I., Tate, Edward W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Academic Press 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615133/
https://ncbi.nlm.nih.gov/pubmed/26334609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.08.025
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