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Topological Analysis of Hedgehog Acyltransferase, a Multipalmitoylated Transmembrane Protein

Hedgehog proteins are secreted morphogens that play critical roles in development and disease. During maturation of the proteins through the secretory pathway, they are modified by the addition of N-terminal palmitic acid and C-terminal cholesterol moieties, both of which are critical for their corr...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Konitsiotis, Antonio D., Jovanović, Biljana, Ciepla, Paulina, Spitaler, Martin, Lanyon-Hogg, Thomas, Tate, Edward W., Magee, Anthony I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319003/
https://ncbi.nlm.nih.gov/pubmed/25505265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.614578
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