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Topological Analysis of Hedgehog Acyltransferase, a Multipalmitoylated Transmembrane Protein
Hedgehog proteins are secreted morphogens that play critical roles in development and disease. During maturation of the proteins through the secretory pathway, they are modified by the addition of N-terminal palmitic acid and C-terminal cholesterol moieties, both of which are critical for their corr...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319003/ https://ncbi.nlm.nih.gov/pubmed/25505265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.614578 |
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