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Click chemistry armed enzyme-linked immunosorbent assay to measure palmitoylation by hedgehog acyltransferase

Hedgehog signaling is critical for correct embryogenesis and tissue development. However, on maturation, signaling is also found to be aberrantly activated in many cancers. Palmitoylation of the secreted signaling protein sonic hedgehog (Shh) by the enzyme hedgehog acyltransferase (Hhat) is required...

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Foilsithe in:Anal Biochem
Main Authors: Lanyon-Hogg, Thomas, Masumoto, Naoko, Bodakh, George, Konitsiotis, Antonio D., Thinon, Emmanuelle, Rodgers, Ursula R., Owens, Raymond J., Magee, Anthony I., Tate, Edward W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Academic Press 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615133/
https://ncbi.nlm.nih.gov/pubmed/26334609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.08.025
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