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Click chemistry armed enzyme-linked immunosorbent assay to measure palmitoylation by hedgehog acyltransferase
Hedgehog signaling is critical for correct embryogenesis and tissue development. However, on maturation, signaling is also found to be aberrantly activated in many cancers. Palmitoylation of the secreted signaling protein sonic hedgehog (Shh) by the enzyme hedgehog acyltransferase (Hhat) is required...
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Foilsithe in: | Anal Biochem |
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Main Authors: | , , , , , , , , |
Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Academic Press
2015
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4615133/ https://ncbi.nlm.nih.gov/pubmed/26334609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2015.08.025 |
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