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DNA end resection is needed for the repair of complex lesions in G1-phase human cells

Repair of DNA double strand breaks (DSBs) is influenced by the chemical complexity of the lesion. Clustered lesions (complex DSBs) are generally considered more difficult to repair and responsible for early and late cellular effects after exposure to genotoxic agents. Resection is commonly used by t...

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Опубликовано в: :Cell Cycle
Главные авторы: Averbeck, Nicole B, Ringel, Oliver, Herrlitz, Maren, Jakob, Burkhard, Durante, Marco, Taucher-Scholz, Gisela
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615131/
https://ncbi.nlm.nih.gov/pubmed/25486192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2015.941743
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