The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling

We previously identified and characterized TELO2 as a human protein that facilitates efficient DNA damage response (DDR) signaling. A subsequent yeast 2-hybrid screen identified LARG; Leukemia-Associated Rho Guanine Nucleotide Exchange Factor (also known as Arhgef12), as a potential novel TELO2 inte...

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Publicado en:Cell Cycle
Autores principales: Beveridge, Ryan D, Staples, Christopher J, Patil, Abhijit A, Myers, Katie N, Maslen, Sarah, Skehel, J Mark, Boulton, Simon J, Collis, Spencer J
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2014
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Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615130/
https://ncbi.nlm.nih.gov/pubmed/25485589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.956529
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