The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling

We previously identified and characterized TELO2 as a human protein that facilitates efficient DNA damage response (DDR) signaling. A subsequent yeast 2-hybrid screen identified LARG; Leukemia-Associated Rho Guanine Nucleotide Exchange Factor (also known as Arhgef12), as a potential novel TELO2 inte...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cell Cycle
Main Authors: Beveridge, Ryan D, Staples, Christopher J, Patil, Abhijit A, Myers, Katie N, Maslen, Sarah, Skehel, J Mark, Boulton, Simon J, Collis, Spencer J
פורמט: Artigo
שפה:Inglês
יצא לאור: Taylor & Francis 2014
נושאים:
Reports
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615130/
https://ncbi.nlm.nih.gov/pubmed/25485589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.956529
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