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Structure of the Rho-specific guanine nucleotide-exchange factor Xpln
Xpln is a guanine nucleotide-exchange factor (GEF) for Rho GTPases. A Dbl homology (DH) domain followed by a pleckstrin homology (PH) domain is a widely adopted GEF-domain architecture. The Xpln structure solely comprises these two domains. Xpln activates RhoA and RhoB, but not RhoC, although their...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
International Union of Crystallography
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509964/ https://ncbi.nlm.nih.gov/pubmed/23192023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112045265 |
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