Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents

DNA damage response (DDR) to double strand breaks is coordinated by 3 phosphatidylinositol 3-kinase-related kinase (PIKK) family members: the ataxia-telangiectasia mutated kinase (ATM), the ATM and Rad3-related (ATR) kinase and the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs). AT...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Cycle
Asıl Yazarlar: Cui, Yuxia, Palii, Stela S, Innes, Cynthia L, Paules, Richard S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2014
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615027/
https://ncbi.nlm.nih.gov/pubmed/25483091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.960729
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