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Genome-Wide Small RNA Sequencing and Gene Expression Analysis Reveals a microRNA Profile of Cancer Susceptibility in ATM-Deficient Human Mammary Epithelial Cells

Deficiencies in the ATM gene are the underlying cause for ataxia telangiectasia, a syndrome characterized by neurological, motor and immunological defects, and a predisposition to cancer. MicroRNAs (miRNAs) are useful tools for cancer profiling and prediction of therapeutic responses to clinical reg...

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Bibliografiske detaljer
Main Authors: Hesse, Jill E., Liu, Liwen, Innes, Cynthia L., Cui, Yuxia, Palii, Stela S., Paules, Richard S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669333/
https://ncbi.nlm.nih.gov/pubmed/23741392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064779
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