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Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit
Exposure of proliferating cells to genotoxic stresses activates a cascade of signaling events termed the DNA damage response (DDR). The DDR preserves genetic stability by detecting DNA lesions, activating cell cycle checkpoints and promoting DNA damage repair. The phosphoinositide 3-kinase-related k...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Landes Bioscience
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646866/ https://ncbi.nlm.nih.gov/pubmed/23462183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24127 |
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